Relevant Papers
2024
Bortolon M., Tsesmelis T., James S., Poiesi F., Del Bue A.
6DGS: 6D Pose Estimation from a Single Image and a 3D Gaussian Splatting Model
European Conference on Computer Vision
2024
Scarpellini G., Fiorini S., Giuliari F., Morerio P., Del Bue A.
DiffAssemble: A Unified Graph-Diffusion Model for 2D and 3D Reassembly
IEEE/CVF Conference on Computer Vision and Pattern Recognition 2024
2022
Giuliari F., Skenderi G., Cristani M., Wang Y., Del Bue A.
Spatial Commonsense Graph for Object Localisation in Partial Scenes
Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition, vol. 2022-June, pp. 19496-19505
Publications
2023
Munafo F., Nigro M., Brindani N., Manigrasso J., Geronimo I., Ottonello G., Armirotti A., De Vivo M.
Computer-aided identification, synthesis, and biological evaluation of DNA polymerase η inhibitors for the treatment of cancer
European Journal of Medicinal Chemistry, vol. 248
2023
Brindani N., Munafo F., Menichetti A., Donati E., Nigro M., Ottonello G., Armirotti A., De Vivo M.
Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors
Bioorganic and Medicinal Chemistry, vol. 80
2022
Munafò F., Nigro M., Brindani N., Manigrasso J., Geronimo I., Ottonello G., Armirotti A., De Vivo M.
Computer-aided identification, synthesis, and biological evaluation of DNA polymerase η inhibitors for the treatment of cancer
European Journal of Medicinal Chemistry
Article
Journal
2022
Munafo F., Donati E., Brindani N., Ottonello G., Armirotti A., De Vivo M.
Quercetin and luteolin are single-digit micromolar inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase
Scientific Reports, vol. 12, (no. 1)
2021
Borgogno M., Savardi A., Manigrasso J., Turci A., Portioli C., Ottonello G., Bertozzi S.M., Armirotti A., Contestabile A., Cancedda L., De Vivo M.
Design, Synthesis,In VitroandIn VivoCharacterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in down Syndrome
Journal of Medicinal Chemistry, vol. 64, (no. 14), pp. 10203-10229
2020
Caputo S., Di Martino S., Cilibrasi V., Tardia P., Mazzonna M., Russo D., Penna I., Summa M., Mandrup Bertozzi S., Realini N., Margaroli N., Migliore M., Ottonello G., Liu M., Lansbury P., Armirotti A., Bertorelli R., Ray S.S., Skerlj R., Scarpelli R.
Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors
Journal of Medicinal Chemistry, vol. 63, (no. 24), pp. 15821-15851
2020
Arencibia J.M., Brindani N., Franco-Ulloa S., Nigro M., Kuriappan J.A., Ottonello G., Bertozzi S.M., Summa M., Girotto S., Bertorelli R., Armirotti A., De Vivo M.
Design, Synthesis, Dynamic Docking, Biochemical Characterization, and in Vivo Pharmacokinetics Studies of Novel Topoisomerase II Poisons with Promising Antiproliferative Activity
Journal of Medicinal Chemistry, vol. 63, (no. 7), pp. 3508-3521
2020
Brindani N., Gianotti A., Giovani S., Giacomina F., Di Fruscia P., Sorana F., Bertozzi S.M., Ottonello G., Goldoni L., Penna I., Russo D., Summa M., Bertorelli R., Ferrera L., Pesce E., Sondo E., Galietta L.J.V., Bandiera T., Pedemonte N., Bertozzi F.
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1 H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators
Journal of Medicinal Chemistry, vol. 63, (no. 19), pp. 11169-11194
2020
Di Martino S., Tardia P., Cilibrasi V., Caputo S., Mazzonna M., Russo D., Penna I., Realini N., Margaroli N., Migliore M., Pizzirani D., Ottonello G., Bertozzi S.M., Armirotti A., Nguyen D., Sun Y., Bongarzone E.R., Lansbury P., Liu M., Skerlj R., Scarpelli R.
Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors
Journal of Medicinal Chemistry, vol. 63, (no. 7), pp. 3634-3664
2020
Di Martino R.M.C., Bottegoni G., Seghetti F., Russo D., Penna I., De Simone A., Ottonello G., Mandrup Bertozzi S., Armirotti A., Bandiera T., Belluti F., Cavalli A.
Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation
ChemMedChem, vol. 15, (no. 11), pp. 949-954
2019
Carli S., Fioravanti G., Armirotti A., Ciarpella F., Prato M., Ottonello G., Salerno M., Scarpellini A., Perrone D., Marchesi E., Ricci D., Fadiga L.
A New Drug Delivery System Based on Tauroursodeoxycholic Acid and PEDOT
Chemistry - A European Journal, vol. 25, (no. 9), pp. 2322-2329
2019
Bertozzi F., Rodríguez-Gimeno A., Berti F., Giraudo A., Bertozzi S.M., Ottonello G., Armirotti A., Caci E., Ferrera L., Tomati V., Sondo E., Pesce E., Pedemonte N., Galietta L.J.V., Bandiera T.
DISCOVERY AND DEVELOPMENT OF A NOVEL NANOMOLAR F508-del CFTR CORRECTOR FOR THE TREATMENT OF CYSTIC FIBROSIS
XXVI National Meeting in Medicinal Chemistry
Poster
Conference
2019
De Vita T., Albani C., Realini N., Migliore M., Basit A., Ottonello G., Cavalli A.
Inhibition of Serine Palmitoyltransferase by a Small Organic Molecule Promotes Neuronal Survival after Astrocyte Amyloid Beta 1-42 Injury
ACS Chemical Neuroscience, vol. 10, (no. 3), pp. 1627-1635
2018
Carli S., Trapella C., Armirotti A., Fantinati A., Ottonello G., Scarpellini A., Prato M., Fadiga L., Ricci D.
A new strategy to deliver Dexamethasone from PEDOT coatings
International Conference on Nanomedicine and Nanobiotechnology
Abstract Report
Conference
2018
Carli S., Trapella C., Armirotti A., Fantinati A., Ottonello G., Scarpellini A., Prato M., Fadiga L., Ricci D.
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT
Chemistry - A European Journal, vol. 24, (no. 41), pp. 10300-10305